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Index > Protein center > FOXM1(Gene name) > Human
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  • FOXM1 (Gene name),
  • Forkhead box protein M1 (Protein name ),  FOXM1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    FOXM1(FKHL16;HFH11;MPP2;WIN);
    Protein name:
    Forkhead box protein M1;
    Alternative:
    Hepatocyte nuclear factor 3 forkhead homolog 11(HFH-11;HNF-3/fork-head homolog 11);Forkhead-related protein FKHL16;MPM-2 reactive phosphoprotein 2;M-phase phosphoprotein 2;Winged-helix factor from INS-1 cells;Transcription factor Trident;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Transcriptional activatory factor. May play a role in the control of cell proliferation.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    763
    Sequence:
    50:
    MKTSPRRPLI | LKRRRLPLPV | QNAPSETSEE | EPKRSPAQQE | SNQAEASKEV | 
    100:
    AESNSCKFPA | GIKIINHPTM | PNTQVVAIPN | NANIHSIITA | LTAKGKESGS | 
    150:
    SGPNKFILIS | CGGAPTQPPG | LRPQTQTSYD | AKRTEVTLET | LGPKPAARDV | 
    200:
    NLPRPPGALC | EQKRETCADG | EAAGCTINNS | LSNIQWLRKM | SSDGLGSRSI | 
    250:
    KQEMEEKENC | HLEQRQVKVE | EPSRPSASWQ | NSVSERPPYS | YMAMIQFAIN | 
    300:
    STERKRMTLK | DIYTWIEDHF | PYFKHIAKPG | WKNSIRHNLS | LHDMFVRETS | 
    350:
    ANGKVSFWTI | HPSANRYLTL | DQVFKPLDPG | SPQLPEHLES | QQKRPNPELR | 
    400:
    RNMTIKTELP | LGARRKMKPL | LPRVSSYLVP | IQFPVNQSLV | LQPSVKVPLP | 
    450:
    LAASLMSSEL | ARHSKRVRIA | PKVLLAEEGI | APLSSAGPGK | EEKLLFGEGF | 
    500:
    SPLLPVQTIK | EEEIQPGEEM | PHLARPIKVE | SPPLEEWPSP | APSFKEESSH | 
    550:
    SWEDSSQSPT | PRPKKSYSGL | RSPTRCVSEM | LVIQHRERRE | RSRSRRKQHL | 
    600:
    LPPCVDEPEL | LFSEGPSTSR | WAAELPFPAD | SSDPASQLSY | SQEVGGPFKT | 
    650:
    PIKETLPISS | TPSKSVLPRT | PESWRLTPPA | KVGGLDFSPV | QTSQGASDPL | 
    700:
    PDPLGLMDLS | TTPLQSAPPL | ESPQRLLSSE | PLDLISVPFG | NSSPSDIDVP | 
    750:
    KPGSPEPQVS | GLAANRSLTE | GLVLDTMNDS | LSKILLDISF | PGLDEDPLGP | 
    763:
    DNINWSQFIP | ELQ
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    SMR:
    KEGG:
    MIM:
    String:
    UniGene:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human Forkhead box protein M1
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    E8912h
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    ELISA Kit for Human Forkhead box protein M1
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    Packing:
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    ELISA Kit for Human Forkhead box protein M1
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    E8912m
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    Packing:
    96T
    CLIA Kit for Human Forkhead box protein M1
    Cat.:
    U8912h
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Forkhead box protein M1
    Cat.:
    U8912r
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Forkhead box protein M1
    Cat.:
    U8912m
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Forkhead box protein M1
    Cat.:
    P8912Rb-h
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Forkhead box protein M1
    Cat.:
    P8912Rb-m
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Forkhead box protein M1
    Cat.:
    P8912Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Forkhead box protein M1
    Monoclonal Antibody for Human Forkhead box protein M1
    Monoclonal Antibody for Human Forkhead box protein M1
    Protein for Human Forkhead box protein M1
    Protein for Human Forkhead box protein M1
    Protein for Human Forkhead box protein M1

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    References
    1. 1.
      "Hepatocyte nuclear factor 3/fork head homolog 11 is expressed in proliferating epithelial and mesenchymal cells of embryonic and adult tissues."
      Ye H. , Kelly T.F. , Samadani U. , Lim L. , Rubio S. , Overdier D.G. , Roebuck K.A. , Costa R.H.
      Mol. Cell. Biol.17:1626-1641(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 2 AND 4)
      tissue: Colon carcinoma.
    2. 2.
      "Molecular analysis of a novel winged helix protein, WIN. Expression pattern, DNA binding property, and alternative splicing within the DNA binding domain."
      Yao K.-M. , Sha M. , Lu Z. , Wong G.G.
      J. Biol. Chem.272:19827-19836(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Pancreatic carcinoma.
      tissue: Testis.
    3. 3.
      NIEHS SNPs program
      Submitted (2005-04) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS GLU-402; LEU-450; PRO-643; ARG-669 AND LEU-673
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2);VARIANT PRO-643
      tissue: Lung.
      tissue: Ovary.
      tissue: Skin.
    5. 5.
      "Cloning of cDNAs for M-phase phosphoproteins recognized by the MPM2 monoclonal antibody and determination of the phosphorylated epitope."
      Westendorf J.M. , Rao P.N. , Gerace L.
      Proc. Natl. Acad. Sci. U.S.A.91:714-718(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 543-763
      tissue: Lymphoblast.
    6. 6.
      "Chk2 mediates stabilization of the FoxM1 transcription factor to stimulate expression of DNA repair genes."
      Tan Y. , Raychaudhuri P. , Costa R.H.
      Mol. Cell. Biol.27:1007-1016(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION IN DNA REPAIR;PHOSPHORYLATION AT SER-376 BY CHEK2
    7. 7.
      "Plk1-dependent phosphorylation of FoxM1 regulates a transcriptional programme required for mitotic progression."
      Fu Z. , Malureanu L. , Huang J. , Wang W. , Li H. , van Deursen J.M. , Tindall D.J. , Chen J.
      Nat. Cell Biol.10:1076-1082(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;PHOSPHORYLATION AT THR-611; SER-693; SER-730 AND SER-739;MUTAGENESIS OF THR-611; SER-693; SER-730 AND SER-739
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-331; THR-620 AND THR-627;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    9. 9.
      "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
      Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-730 AND SER-739;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    10. 10.
      "Structure of the FoxM1 DNA-recognition domain bound to a promoter sequence."
      Littler D.R. , Alvarez-Fernandez M. , Stein A. , Hibbert R.G. , Heidebrecht T. , Aloy P. , Medema R.H. , Perrakis A.
      Nucleic Acids Res.38:4527-4538(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.21 ANGSTROMS) OF 222-360 IN COMPLEX WITH PROMOTER DNA;FUNCTION
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